Enzyme inhibitor

5-Amino-1MQ

5-Amino-1MQ is a small, non-peptide quinolinium molecule with an amino group at position 5 and methylation at the ring nitrogen. In preclinical models, it binds to the catalytic site of nicotinamide N-methyltransferase and inhibits that enzyme. It has been investigated in models of nicotinamide metabolism and cellular metabolic regulation in in vitro studies.

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10 mg$1,188 MXN / unit

$1,188 MXN / unit

Mass: 10 mg

In stock · SKU AMQ-10

Quantity

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For laboratory research only. Not for human or veterinary use.

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Research context & mechanism

NNMT transfers a methyl group from S-adenosylmethionine to nicotinamide. Its inhibition modulates nicotinamide availability in the dinucleotide salvage pathway in cellular models.

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name: 5-amino-1-methylquinolin-1-ium (iodide salt)
Sequence: Not available
Molecular formula: Not available
Molecular weight: Not available
CAS number: Not available
Form: Lyophilized powder
Appearance: White to pale yellow solid
Purity specification: Declared in the batch certificate
Identity: Declared in the batch certificate
Solubility: Soluble in sterile water
Storage: −20 °C, protected from light
Stability after reconstitution: Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Certificate results are accessed with your order details; if documentation is available on request, contact support before relying on it.

Consult batch certificates How to read documentation

Laboratory handling

Reconstitution: Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
Storage: Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
Protective equipment: Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.