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Pureza
Tirzepatide, 10 mg, Pureza research material

Metabolic peptide

Tirzepatide

Tirzepatide is a synthetic 39-amino-acid peptide derived from the GIP sequence, with acylation at a lysine residue. In research literature, it binds to GIP and GLP-1 receptors and acts as a dual agonist of both pathways. It has been studied in models of incretin signaling and metabolic regulation in preclinical research.

Select a variant

$1,296 MXN / unit

Mass: 10 mg

In stock · SKU TIRZ-10

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For laboratory research only. Not for human or veterinary use.

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Research context & mechanism

The molecule has differential affinity for GIPR and GLP-1R, both of which are Gs protein-coupled receptors. Activation of these receptors modulates cyclic AMP production in cellular models.

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name
Acylated GIP analog with dual activity at GIPR and GLP-1R
Sequence
Not available
Molecular formula
C225H348N48O68
Molecular weight
4813.5 Da
CAS number
2023788-19-2
Form
Lyophilized powder
Appearance
White to off-white solid
Purity specification
Declared in the batch certificate
Identity
Declared in the batch certificate
Solubility
Soluble in sterile water and bacteriostatic water
Storage
−20 °C, protected from light
Stability after reconstitution
Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Certificate results are accessed with your order details; if documentation is available on request, contact support before relying on it.

Consult batch certificates How to read documentation

Laboratory handling

Reconstitution
Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
Storage
Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
Protective equipment
Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.

Research references

  1. Tirzepatide Once Weekly for the Treatment of Obesity.

    N Engl J Med · 2022 · PMID 35658024

  2. Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes.

    N Engl J Med · 2021 · PMID 34170647

  3. Tirzepatide: A Review in Type 2 Diabetes.

    Drugs · 2024 · PMID 38388874

  4. Subcutaneously administered tirzepatide vs semaglutide for adults with type 2 diabetes: a systematic review and network meta-analysis of randomised controlled trials.

    Diabetologia · 2024 · PMID 38613667

  5. LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept.

    Mol Metab · 2018 · PMID 30473097

  6. Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist.

    JCI Insight · 2020 · PMID 32730231

Frequently asked questions

How is Tirzepatide supplied?

Tirzepatide is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.

How is Tirzepatide stored in the laboratory?

Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.

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