
Metabolic peptide
Retatrutide
Retatrutide is a synthetic acylated peptide derived from the structure of glucose-dependent insulinotropic polypeptide. In research models, it binds to GIP, GLP-1 and glucagon receptors and acts as an agonist of these three signaling pathways. It has been studied in models of metabolic regulation and body composition in preclinical research.
$2,070 MXN / unit
Mass: 10 mg
In stock · SKU RETA-10
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For laboratory research only. Not for human or veterinary use.
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Shipping termsResearch context & mechanism
In research models, the molecule acts on three G protein-coupled receptors in the secretin family. Its lipid chain prolongs association with albumin, modifying the exposure profile described in preclinical literature.
Technical specifications
Reference specifications describe the material. They do not replace the analytical results for a specific batch.
- Chemical name
- Acylated GIP peptide analog with activity at GLP-1R and GCGR
- Sequence
- Not available
- Molecular formula
- Not available
- Molecular weight
- Not available
- CAS number
- 2381089-83-2
- Form
- Lyophilized powder
- Appearance
- White to off-white solid
- Purity specification
- Declared in the batch certificate
- Identity
- Declared in the batch certificate
- Solubility
- Soluble in sterile water and bacteriostatic water
- Storage
- −20 °C, protected from light
- Stability after reconstitution
- Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol
Batch documentation
Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Certificate results are accessed with your order details; if documentation is available on request, contact support before relying on it.
Consult batch certificates How to read documentationLaboratory handling
- Reconstitution
- Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
- Storage
- Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
- Protective equipment
- Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.
Research references
- Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial
N Engl J Med · 2023 · PMID 37366315
- Efficacy and safety of retatrutide, a GIP, GLP-1, and glucagon receptor agonist, in people with type 2 diabetes and inadequate glycaemic control with diet and exercise (TRANSCEND-T2D-1): a double-blind, randomised, phase 3 trial
Lancet · 2026 · PMID 42250575
- Comparative effects of drugs for adults with overweight or obesity: systematic review and network meta-analysis
BMJ · 2026 · PMID 42419792
- Retatrutide in type 2 diabetes mellitus and obesity: an overview
Expert Rev Clin Pharmacol · 2026 · PMID 41785010
- LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept
Cell Metab · 2022 · PMID 35985340
- LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial
Lancet · 2022 · PMID 36354040
Frequently asked questions
How is Retatrutide supplied?
Retatrutide is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.
How is Retatrutide stored in the laboratory?
Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.



