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Pureza
Retatrutide, 10 mg, Pureza research material

Metabolic peptide

Retatrutide

Retatrutide is a synthetic acylated peptide derived from the structure of glucose-dependent insulinotropic polypeptide. In research models, it binds to GIP, GLP-1 and glucagon receptors and acts as an agonist of these three signaling pathways. It has been studied in models of metabolic regulation and body composition in preclinical research.

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$2,070 MXN / unit

Mass: 10 mg

In stock · SKU RETA-10

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For laboratory research only. Not for human or veterinary use.

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Research context & mechanism

In research models, the molecule acts on three G protein-coupled receptors in the secretin family. Its lipid chain prolongs association with albumin, modifying the exposure profile described in preclinical literature.

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name
Acylated GIP peptide analog with activity at GLP-1R and GCGR
Sequence
Not available
Molecular formula
Not available
Molecular weight
Not available
CAS number
2381089-83-2
Form
Lyophilized powder
Appearance
White to off-white solid
Purity specification
Declared in the batch certificate
Identity
Declared in the batch certificate
Solubility
Soluble in sterile water and bacteriostatic water
Storage
−20 °C, protected from light
Stability after reconstitution
Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Certificate results are accessed with your order details; if documentation is available on request, contact support before relying on it.

Consult batch certificates How to read documentation

Laboratory handling

Reconstitution
Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
Storage
Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
Protective equipment
Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.

Research references

  1. Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial

    N Engl J Med · 2023 · PMID 37366315

  2. Efficacy and safety of retatrutide, a GIP, GLP-1, and glucagon receptor agonist, in people with type 2 diabetes and inadequate glycaemic control with diet and exercise (TRANSCEND-T2D-1): a double-blind, randomised, phase 3 trial

    Lancet · 2026 · PMID 42250575

  3. Comparative effects of drugs for adults with overweight or obesity: systematic review and network meta-analysis

    BMJ · 2026 · PMID 42419792

  4. Retatrutide in type 2 diabetes mellitus and obesity: an overview

    Expert Rev Clin Pharmacol · 2026 · PMID 41785010

  5. LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept

    Cell Metab · 2022 · PMID 35985340

  6. LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial

    Lancet · 2022 · PMID 36354040

Frequently asked questions

How is Retatrutide supplied?

Retatrutide is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.

How is Retatrutide stored in the laboratory?

Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.

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