Metabolic peptide

Semaglutide

Semaglutide is a glucagon-like peptide-1 analog with substitutions at positions 8 and 34 and a fatty acid chain attached through a spacer. In preclinical models, it binds to the GLP-1 receptor and acts as an agonist of that pathway. It has been investigated in models of glucose homeostasis and metabolic regulation in animal studies.

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5 mg$2,100 MXN / unit10 mg$3,990 MXN / unit

$2,100 MXN / unit

Mass: 5 mg

In stock · SKU SEMA-05

Quantity

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For laboratory research only. Not for human or veterinary use.

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Research context & mechanism

Replacing alanine with Aib at position 8 reduces degradation by dipeptidyl peptidase 4 in in vitro studies. Acylation promotes albumin binding and modifies the kinetics of receptor exposure in experimental models.

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name: N-epsilon-26-{2-[2-(2-{2-[2-(2-{(4S)-4-carboxy-4-[(17-carboxyheptadecanoyl)amino]butanoyl}amino)ethoxy]ethoxy}acetyl)amino]ethoxy}ethoxy-acetyl-[8-(2-amino-2-methylpropanoyl), 34-arginine]-GLP-1-(7-37) acid
Sequence: Not available
Molecular formula: C187H291N45O59
Molecular weight: 4113.58 Da
CAS number: 910463-68-2
Form: Lyophilized powder
Appearance: White to off-white solid
Purity specification: Declared in the batch certificate
Identity: Declared in the batch certificate
Solubility: Soluble in sterile water and bacteriostatic water
Storage: −20 °C, protected from light
Stability after reconstitution: Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Certificate results are accessed with your order details; if documentation is available on request, contact support before relying on it.

Consult batch certificates How to read documentation

Laboratory handling

Reconstitution: Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
Storage: Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
Protective equipment: Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.