Melanocortin analog

Melanotan-2

Melanotan-2 is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone, cyclized through a lactam bridge. In preclinical models, it binds to several melanocortin receptors, including MC1R, MC3R and MC4R, with a nonselective profile. It has been investigated in models of melanocortin signaling in rodent studies.

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10 mg$1,199 MXN / unit

$1,199 MXN / unit

Mass: 10 mg

In stock · SKU MT2-10

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For laboratory research only. Not for human or veterinary use.

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Research context & mechanism

Cyclization restricts the peptide's conformation and modifies its relative affinity for receptor subtypes. All of these are Gs protein-coupled receptors in cellular models.

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Molecular formula: C50H69N15O9
Molecular weight: 1024.2 Da
CAS number: 121062-08-6
Form: Lyophilized powder
Appearance: White to off-white solid
Purity specification: Declared in the batch certificate
Identity: Declared in the batch certificate
Solubility: Soluble in sterile water and bacteriostatic water
Storage: −20 °C, protected from light
Stability after reconstitution: Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Certificate results are accessed with your order details; if documentation is available on request, contact support before relying on it.

Consult batch certificates How to read documentation

Laboratory handling

Reconstitution: Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
Storage: Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
Protective equipment: Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.