Skip to content
Pureza
Melanotan-1, 10 mg, Pureza research material

Melanocortin analog

Melanotan-1

Melanotan-1 is a synthetic analog of alpha-melanocyte-stimulating hormone, with norleucine and D-phenylalanine substitutions described in the literature as determinants of its stability. NDP-alpha-MSH has been studied in in vitro melanocortin receptor binding assays and as a reference for comparing structural variants across subtypes. It has been studied in models of melanogenesis in in vitro studies.

Select a variant

$1,080 MXN / unit

Mass: 10 mg

In stock · SKU MT1-10

Prices in Mexican pesos. Cart and secure checkout are currently in Spanish. Shipping and any applicable discounts are shown before payment.

For laboratory research only. Not for human or veterinary use.

Shipping within Mexico · Free from $2,500 MXN.

Shipping protection included: report damage with photos within 24 hours of delivery for one replacement.

Shipping terms

Research context & mechanism

MC1R is a Gs protein-coupled receptor present in melanocytes. Its activation modulates the cyclic AMP pathway and tyrosinase expression in cellular models.

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name
[Nle4, D-Phe7]-alpha-MSH
Sequence
Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Molecular formula
C78H111N21O19
Molecular weight
1646.9 Da
CAS number
75921-69-6
Form
Lyophilized powder
Appearance
White to off-white solid
Purity specification
Declared in the batch certificate
Identity
Declared in the batch certificate
Solubility
Soluble in sterile water and bacteriostatic water
Storage
−20 °C, protected from light
Stability after reconstitution
Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Certificate results are accessed with your order details; if documentation is available on request, contact support before relying on it.

Consult batch certificates How to read documentation

Laboratory handling

Reconstitution
Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
Storage
Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
Protective equipment
Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.

Research references

  1. Afamelanotide for Erythropoietic Protoporphyria.

    N Engl J Med · 2015 · PMID 26132941

  2. Afamelanotide and narrowband UV-B phototherapy for the treatment of vitiligo: a randomized multicenter trial.

    JAMA Dermatol · 2015 · PMID 25230094

  3. Pharmacokinetics and Pharmacodynamics of Afamelanotide and its Clinical Use in Treating Dermatologic Disorders.

    Clin Pharmacokinet · 2017 · PMID 28063031

  4. Risks of unregulated use of alpha-melanocyte-stimulating hormone analogues: a review.

    Int J Dermatol · 2017 · PMID 28266027

Frequently asked questions

How is Melanotan-1 supplied?

Melanotan-1 is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.

How is Melanotan-1 stored in the laboratory?

Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.

Related research materials