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Pureza
Selank, 5 mg, Pureza research material

Neuroactive peptide

Selank

Selank is a synthetic heptapeptide formed by the tuftsin fragment extended with the stabilizing Pro-Gly-Pro sequence. In research models, it has been described as acting on neurotransmission pathways associated with monoaminergic systems and neurotrophic factor expression. It has been investigated in models of exploratory behavior in rodent studies.

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$673 MXN / unit

Mass: 5 mg

In stock · SKU SEL-05

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For laboratory research only. Not for human or veterinary use.

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Research context & mechanism

In in vitro studies with brain membranes, Selank modified the binding of labeled GABA; the authors interpreted the findings as compatible with allosteric modulation. The assay does not establish an exclusive target for all its experimental responses.

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name
Threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline
Sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Molecular formula
C33H57N11O9
Molecular weight
751.88 Da
CAS number
129954-34-3
Form
Lyophilized powder
Appearance
White to off-white solid
Purity specification
Declared in the batch certificate
Identity
Declared in the batch certificate
Solubility
Soluble in sterile water and bacteriostatic water
Storage
−20 °C, protected from light
Stability after reconstitution
Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Certificate results are accessed with your order details; if documentation is available on request, contact support before relying on it.

Consult batch certificates How to read documentation

Laboratory handling

Reconstitution
Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
Storage
Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
Protective equipment
Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.

Research references

  1. [A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders].

    Zh Nevrol Psikhiatr Im S S Korsakova · 2014 · PMID 25176261

  2. Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity.

    Protein Pept Lett · 2018 · PMID 30255741

  3. Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission.

    Front Pharmacol · 2016 · PMID 26924987

  4. The temporary dynamics of inflammation-related genes expression under tuftsin analog Selank action.

    Mol Immunol · 2014 · PMID 24291245

Frequently asked questions

How is Selank supplied?

Selank is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.

How is Selank stored in the laboratory?

Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.

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