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Pureza
Epitalon, 10 mg, Pureza research material

Synthetic AEDG tetrapeptide

Epitalon

Epitalon is the synthetic tetrapeptide Ala-Glu-Asp-Gly, developed from the amino acid composition of the pineal extract Epithalamin. In research models, it has been described as acting on expression of the catalytic subunit of telomerase and on pathways associated with pineal regulation. It has been investigated in models of circadian rhythm and cellular senescence in rodent studies.

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$621 MXN / unit

Mass: 10 mg

In stock · SKU EPI-10

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For laboratory research only. Not for human or veterinary use.

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Research context & mechanism

In vitro studies have examined changes in telomerase expression and activity, as well as markers of cellular differentiation. According to the literature, modeling of interactions with histones proposes a possible mechanism without establishing a single target.

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name
L-alanyl-L-glutamyl-L-aspartyl-glycine
Sequence
Ala-Glu-Asp-Gly
Molecular formula
C14H22N4O9
Molecular weight
390.35 Da
CAS number
307297-39-8
Form
Lyophilized powder
Appearance
White to off-white solid
Purity specification
Declared in the batch certificate
Identity
Declared in the batch certificate
Solubility
Soluble in sterile water and bacteriostatic water
Storage
−20 °C, protected from light
Stability after reconstitution
Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Certificate results are accessed with your order details; if documentation is available on request, contact support before relying on it.

Consult batch certificates How to read documentation

Laboratory handling

Reconstitution
Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
Storage
Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
Protective equipment
Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.

Research references

  1. Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties

    Int J Mol Sci · 2025 · PMID 40141333

  2. Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity

    Biogerontology · 2025 · PMID 40908429

  3. AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism

    Molecules · 2020 · PMID 32019204

  4. Therapeutic peptides in gerontology: mechanisms and applications for healthy aging

    Front Aging · 2026 · PMID 42021992

Frequently asked questions

How is Epitalon supplied?

Epitalon is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.

How is Epitalon stored in the laboratory?

Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.

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