
Synthetic AEDG tetrapeptide
Epitalon
Epitalon is the synthetic tetrapeptide Ala-Glu-Asp-Gly, developed from the amino acid composition of the pineal extract Epithalamin. In research models, it has been described as acting on expression of the catalytic subunit of telomerase and on pathways associated with pineal regulation. It has been investigated in models of circadian rhythm and cellular senescence in rodent studies.
$621 MXN / unit
Mass: 10 mg
In stock · SKU EPI-10
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For laboratory research only. Not for human or veterinary use.
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Shipping termsResearch context & mechanism
In vitro studies have examined changes in telomerase expression and activity, as well as markers of cellular differentiation. According to the literature, modeling of interactions with histones proposes a possible mechanism without establishing a single target.
Technical specifications
Reference specifications describe the material. They do not replace the analytical results for a specific batch.
- Chemical name
- L-alanyl-L-glutamyl-L-aspartyl-glycine
- Sequence
- Ala-Glu-Asp-Gly
- Molecular formula
- C14H22N4O9
- Molecular weight
- 390.35 Da
- CAS number
- 307297-39-8
- Form
- Lyophilized powder
- Appearance
- White to off-white solid
- Purity specification
- Declared in the batch certificate
- Identity
- Declared in the batch certificate
- Solubility
- Soluble in sterile water and bacteriostatic water
- Storage
- −20 °C, protected from light
- Stability after reconstitution
- Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol
Batch documentation
Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Certificate results are accessed with your order details; if documentation is available on request, contact support before relying on it.
Consult batch certificates How to read documentationLaboratory handling
- Reconstitution
- Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
- Storage
- Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
- Protective equipment
- Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.
Research references
- Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties
Int J Mol Sci · 2025 · PMID 40141333
- Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity
Biogerontology · 2025 · PMID 40908429
- AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism
Molecules · 2020 · PMID 32019204
- Therapeutic peptides in gerontology: mechanisms and applications for healthy aging
Front Aging · 2026 · PMID 42021992
Frequently asked questions
How is Epitalon supplied?
Epitalon is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.
How is Epitalon stored in the laboratory?
Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.
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