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CJC-1295 No-DAC, 10 mg, Pureza research material

GHRH analog

CJC-1295 No-DAC

CJC-1295 No-DAC is a tetrasubstituted analog of the 1-29 fragment of growth hormone-releasing hormone, without the albumin affinity complex. In preclinical models, it binds to the GHRH receptor and acts as an agonist of that pathway in the anterior pituitary. It has been investigated in models of somatotropic axis signaling in rodent studies.

Select a variant

$1,150 MXN / unit

Mass: 10 mg

In stock · SKU CJCN-10

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For laboratory research only. Not for human or veterinary use.

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Research context & mechanism

Substitutions at positions 2, 8, 15 and 27 reduce enzymatic degradation of the sequence in in vitro studies. Activation of the GHRH receptor increases cyclic AMP in cellular models.

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name
[D-Ala2, Gln8, Ala15, Leu27]-GHRH(1-29) amide
Sequence
Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
Molecular formula
Not available
Molecular weight
Not available
CAS number
863288-34-0
Form
Lyophilized powder
Appearance
White to off-white solid
Purity specification
Declared in the batch certificate
Identity
Declared in the batch certificate
Solubility
Soluble in sterile water and bacteriostatic water
Storage
−20 °C, protected from light
Stability after reconstitution
Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Certificate results are accessed with your order details; if documentation is available on request, contact support before relying on it.

Consult batch certificates How to read documentation

Laboratory handling

Reconstitution
Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
Storage
Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
Protective equipment
Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.

Research references

The bibliography brings together work on the analog with DAC and analytical studies that distinguish the two variants. PMID 34665524 includes CJC-1295 without DAC in in vitro research; it does not establish its exposure in humans. Findings for the variant with DAC do not carry over to this preparation.

  1. Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog

    Endocrinology · 2005 · PMID 15817669

  2. The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration

    Front Endocrinol (Lausanne) · 2026 · PMID 42395176

  3. Advances in the detection of growth hormone releasing hormone synthetic analogs

    Drug Test Anal · 2021 · PMID 34665524

  4. Glycine-modified growth hormone secretagogues identified in seized doping material

    Drug Test Anal · 2019 · PMID 30136411

  5. Identification of CJC-1295, a growth-hormone-releasing peptide, in an unknown pharmaceutical preparation

    Drug Test Anal · 2010 · PMID 21204297

Frequently asked questions

How is CJC-1295 No-DAC supplied?

CJC-1295 No-DAC is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.

How is CJC-1295 No-DAC stored in the laboratory?

Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.

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